Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia

Por Coskun, Pinar E., Busciglio, Jorge
Publicado em 2012

Rapid onset mediastinal hematoma due to vertebral fracture and review of relevant literature

Por Koksal, Vaner, Coskun, Selcuk, Coskun, Pinar Koksal
Publicado no Turk J Emerg Med (2016)

Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum

Por Coskun, Pinar E., Ruiz-Pesini, Eduardo, Wallace, Douglas C.
Publicado em 2003

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

Por Coskun, Pinar E., Beal, M. Flint, Wallace, Douglas C.
Publicado em 2004

A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome

Por Garcia, Octavio, Torres, Maria, Helguera, Pablo, Coskun, Pinar, Busciglio, Jorge
Publicado em 2010

Increased mitochondrial oxidative stress in the Sod2 (+/−) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

Por Kokoszka, Jason E., Coskun, Pinar, Esposito, Luke A., Wallace, Douglas C.
Publicado em 2001

A Mitochondrial Etiology of Alzheimer and Parkinson Disease

Por Coskun, Pinar, Wyrembak, Joanne, Schriner, Sam, Chen, Hsiao-Wen, Marciniack, Christine, LaFerla, Frank, Wallace, Douglas C.
Publicado em 2011

Systemic Mitochondrial Dysfunction and the Etiology of Alzheimer's Disease and Down Syndrome Dementia

Por Coskun, Pinar E., Wyrembak, Joanne, Derbereva, Olga, Melkonian, Goar, Doran, Eric, Lott, Ira T., Head, Elizabeth, Cotman, Carl W., Wallace, Douglas C.
Publicado em 2010

MITOCHIP Assessment of Differential Gene Expression in the Skeletal Muscle of Ant1 Knockout Mice: Coordinate Regulation of OXPHOS, Antioxidant, and Apoptotic Genes

Por Subramaniam, Vaidya, Golik, Pawel, Murdock, Deborah G., Levy, Shawn, Kerstann, Keith W., Coskun, Pinar E., Melkonian, Goarik A., Wallace, Douglas C.
Publicado no Biochim Biophys Acta (2008)

Swedish Alzheimer Mutation Induces Mitochondrial Dysfunction Mediated by HSP60 Mislocalization of Amyloid Precursor Protein (APP) and Beta-Amyloid

Por Walls, Ken Carlson, Coskun, Pinar, Gallegos-Perez, Jose Luis, Zadourian, Nineli, Freude, Kristine, Rasool, Suhail, Blurton-Jones, Mathew, Green, Kim Nicholas, LaFerla, Frank Michael
Publicado em 2012

A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations

Por Fan, Weiwei, Waymire, Katrina G., Narula, Navneet, Li, Peng, Rocher, Christophe, Coskun, Pinar E., Vannan, Mani A., Narula, Jagat, MacGregor, Grant R., Wallace, Douglas C.
Publicado em 2008

Differential Gene Expression Reveals Mitochondrial Dysfunction in an Imprinting Center Deletion Mouse Model of Prader–Willi Syndrome

Por Yazdi, Puya G., Su, Hailing, Ghimbovschi, Svetlana, Fan, Weiwei, Coskun, Pinar E., Nalbandian, Angèle, Knoblach, Susan, Resnick, James L., Hoffman, Eric, Wallace, Douglas C., Kimonis, Virginia E.
Publicado em 2013

Mitochondrial dysfunction in CA1 hippocampal neurons of the Ube3a deficient mouse model for Angelman syndrome

Por Su, Hailing, Fan, Weiwei, Coskun, Pinar E., Vesa, Jouni, Gold, June-Anne, Jiang, Yong-Hui, Potluri, Prasanth, Procaccio, Vincent, Acab, Allan, Weiss, John H., Wallace, Douglas C., Kimonis, Virginia E.
Publicado em 2009

Mitochondrial disease in superoxide dismutase 2 mutant mice

Por Melov, Simon, Coskun, Pinar, Patel, Manisha, Tuinstra, Robbyn, Cottrell, Barbara, Jun, Albert S., Zastawny, Tomsz H., Dizdaroglu, Miral, Goodman, Stephen I., Huang, Ting-Ting, Miziorko, Henry, Epstein, Charles J., Wallace, Douglas C.
Publicado em 1999

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

Por Peiris, Heshan, Duffield, Michael D., Fadista, Joao, Jessup, Claire F., Kashmir, Vinder, Genders, Amanda J., McGee, Sean L., Martin, Alyce M., Saiedi, Madiha, Morton, Nicholas, Carter, Roderick, Cousin, Michael A., Kokotos, Alexandros C., Oskolkov, Nikolay, Volkov, Petr, Hough, Tertius A., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Busciglio, Jorge, Coskun, Pinar E., Becker, Ann, Belichenko, Pavel V., Mobley, William C., Ryan, Michael T., Chan, Jeng Yie, Laybutt, D. Ross, Coates, P. Toby, Yang, Sijun, Ling, Charlotte, Groop, Leif, Pritchard, Melanie A., Keating, Damien J.
Publicado no PLoS Genet (2016)