Mitochondrial dysfunction in CA1 hippocampal neurons of the Ube3a deficient mouse model for Angelman syndrome

Angelman syndrome (AS) is a severe neurological disorder caused by a deficiency of ubiquitin protein ligase E3A (Ube3a), but the pathophysiology of the disease remains unknown. We now report that in the brains of AS mice in which the maternal Ube3a allele is mutated (m-) and the paternal allele is p...

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Main Authors: Su, Hailing, Fan, Weiwei, Coskun, Pinar E., Vesa, Jouni, Gold, June-Anne, Jiang, Yong-Hui, Potluri, Prasanth, Procaccio, Vincent, Acab, Allan, Weiss, John H., Wallace, Douglas C., Kimonis, Virginia E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888840/
https://ncbi.nlm.nih.gov/pubmed/19563863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.06.079
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