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mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination

The role of mitochondrial DNA (mtDNA) mutations and mtDNA recombination in cancer cell proliferation and developmental biology remains controversial. While analyzing the mtDNAs of several mouse L cell lines, we discovered that every cell line harbored multiple mtDNA mutants. These included four miss...

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Hlavní autoři: Fan, Weiwei, Lin, Chun Shi, Potluri, Prasanth, Procaccio, Vincent, Wallace, Douglas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289886/
https://ncbi.nlm.nih.gov/pubmed/22345519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.175802.111
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