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mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination

The role of mitochondrial DNA (mtDNA) mutations and mtDNA recombination in cancer cell proliferation and developmental biology remains controversial. While analyzing the mtDNAs of several mouse L cell lines, we discovered that every cell line harbored multiple mtDNA mutants. These included four miss...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fan, Weiwei, Lin, Chun Shi, Potluri, Prasanth, Procaccio, Vincent, Wallace, Douglas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289886/
https://ncbi.nlm.nih.gov/pubmed/22345519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.175802.111
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