Wird geladen...

High Throughput Gene Complementation Screening Permits Identification of a Mammalian Mitochondrial Protein Synthesis (ρ(−)) Mutant

To identify nuclear DNA (nDNA) oxidative phosphorylation (OXPHOS) gene mutations using cultured cells, we have developed a complementation system based on retroviral transduction with a full length cDNA expression library and selection for OXHOS function by growth in galactose. We have used this sys...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Potluri, Prasanth, Procaccio, Vincent, Scheffler, Immo E, Wallace, Douglas C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893908/
https://ncbi.nlm.nih.gov/pubmed/26946086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2016.02.021
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!