A carregar...
A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations
The majority of mitochondrial DNA (mtDNA) mutations that cause human disease are mild to moderately deleterious, yet many random mtDNA mutations would be expected to be severe. To determine the fate of the more severe mtDNA mutations, we introduced mtDNAs containing two mutations that affect oxidati...
Na minha lista:
| Main Authors: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049809/ https://ncbi.nlm.nih.gov/pubmed/18276892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1147786 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|