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Swedish Alzheimer Mutation Induces Mitochondrial Dysfunction Mediated by HSP60 Mislocalization of Amyloid Precursor Protein (APP) and Beta-Amyloid

Alzheimer disease (AD) is a complex disorder that involves numerous cellular and subcellular alterations including impairments in mitochondrial homeostasis. To better understand the role of mitochondrial dysfunction in the pathogenesis of AD, we analyzed brains from clinically well-characterized hum...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Walls, Ken Carlson, Coskun, Pinar, Gallegos-Perez, Jose Luis, Zadourian, Nineli, Freude, Kristine, Rasool, Suhail, Blurton-Jones, Mathew, Green, Kim Nicholas, LaFerla, Frank Michael
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436283/
https://ncbi.nlm.nih.gov/pubmed/22753410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365890
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