Swedish Alzheimer Mutation Induces Mitochondrial Dysfunction Mediated by HSP60 Mislocalization of Amyloid Precursor Protein (APP) and Beta-Amyloid

Alzheimer disease (AD) is a complex disorder that involves numerous cellular and subcellular alterations including impairments in mitochondrial homeostasis. To better understand the role of mitochondrial dysfunction in the pathogenesis of AD, we analyzed brains from clinically well-characterized hum...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Walls, Ken Carlson, Coskun, Pinar, Gallegos-Perez, Jose Luis, Zadourian, Nineli, Freude, Kristine, Rasool, Suhail, Blurton-Jones, Mathew, Green, Kim Nicholas, LaFerla, Frank Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436283/
https://ncbi.nlm.nih.gov/pubmed/22753410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365890
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados