Soluble Amyloid Precursor Protein Induces Rapid Neural Differentiation of Human Embryonic Stem Cells

Human embryonic stem cells (hESCs) offer tremendous potential for not only treating neurological disorders but also for their ability to serve as vital reagents to model and investigate human disease. To further our understanding of a key protein involved in Alzheimer disease pathogenesis, we stably...

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Bibliographic Details
Main Authors: Freude, Kristine K., Penjwini, Mahmud, Davis, Joy L., LaFerla, Frank M., Blurton-Jones, Mathew
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129207/
https://ncbi.nlm.nih.gov/pubmed/21606494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227421
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