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Soluble Aβ Promotes Wild-Type Tau Pathology In Vivo
Growing evidence suggests that soluble Aβ species can drive Alzheimer disease (AD) pathogenesis by inducing a cascade of events including tau hyperphosphorylation, proteasome impairment, and synaptic dysfunction. However, these studies have relied largely on in vitro approaches to examine the role o...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Society for Neuroscience
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586232/ https://ncbi.nlm.nih.gov/pubmed/23197725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0172-12.2012 |
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