Soluble Aβ Promotes Wild-Type Tau Pathology In Vivo

Growing evidence suggests that soluble Aβ species can drive Alzheimer disease (AD) pathogenesis by inducing a cascade of events including tau hyperphosphorylation, proteasome impairment, and synaptic dysfunction. However, these studies have relied largely on in vitro approaches to examine the role o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chabrier, Meredith A., Blurton-Jones, Mathew, Agazaryan, Andranik A., Nerhus, Joy L., Martinez-Coria, Hilda, LaFerla, Frank M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2012
Pynciau:
Brief Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586232/
https://ncbi.nlm.nih.gov/pubmed/23197725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0172-12.2012
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg