Forum Original Research Communication: Frataxin, Iron–Sulfur Clusters, Heme, ROS, and Aging

par NAPOLI, ELEONORA, TARONI, FRANCO, CORTOPASSI, GINO A.
Publié 2006

Biosensor plates detect mitochondrial physiological regulators and mutations in vivo

par Rolo, Anabela P., Palmeira, Carlos M., Cortopassi, Gino A.
Publié 2008

Neurobehavioral deficits in the KIKO mouse model of Friedreich’s ataxia

par McMackin, Marissa Z., Henderson, Chelsea K., Cortopassi, Gino A.
Publié dans Behav Brain Res (2016)

Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression

par Song, Lanying, Shan, Yuxi, Lloyd, K.C. Kent, Cortopassi, Gino A.
Publié 2012

The Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant Cells

par Datta, Sandipan, Baudouin, Christophe, Brignole-Baudouin, Francoise, Denoyer, Alexandre, Cortopassi, Gino A.
Publié dans Invest Ophthalmol Vis Sci (2017)

Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules

par Yu, Alfred K, Datta, Sandipan, McMackin, Marissa Z, Cortopassi, Gino A
Publié dans Hum Mol Genet (2017)

Key Glycolytic Enzyme Activities of Skeletal Muscle Are Decreased under Fed and Fasted States in Mice with Knocked Down Levels of Shc Proteins

par Hagopian, Kevork, Tomilov, Alexey A., Kim, Kyoungmi, Cortopassi, Gino A., Ramsey, Jon J.
Publié dans PLoS One (2015)

Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression

par Chowanadisai, Winyoo, Bauerly, Kathryn A., Tchaparian, Eskouhie, Wong, Alice, Cortopassi, Gino A., Rucker, Robert B.
Publié 2010

Frataxin deficiency impairs mitochondrial biogenesis in cells, mice and humans

par Jasoliya, Mittal J., McMackin, Marissa Z., Henderson, Chelsea K., Perlman, Susan L., Cortopassi, Gino A.
Publié dans Hum Mol Genet (2017)

Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria

par Duveau, Damien Y., Arce, Pablo M., Schoenfeld, Robert A., Raghav, Nidhi, Cortopassi, Gino A., Hecht, Sidney M.
Publié 2010

Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver

par Hagopian, Kevork, Kim, Kyoungmi, López-Dominguez, José Alberto, Tomilov, Alexey A., Cortopassi, Gino A., Ramsey, Jon J.
Publié dans Biochem Biophys Rep (2016)

Dysregulation of Glutamine Transporter SNAT1 in Rett Syndrome Microglia: A Mechanism for Mitochondrial Dysfunction and Neurotoxicity

par Jin, Lee-Way, Horiuchi, Makoto, Wulff, Heike, Liu, Xiao-Bo, Cortopassi, Gino A., Erickson, Jeffrey D., Maezawa, Izumi
Publié dans J Neurosci (2015)

Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse

par Yu, Alfred K., Song, Lanying, Murray, Karl D., van der List, Deborah, Sun, Chao, Shen, Yan, Xia, Zhengui, Cortopassi, Gino A.
Publié dans Hum Mol Genet (2015)

Potential biomarker identification for Friedreich’s ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion

par McMackin, Marissa Z., Durbin-Johnson, Blythe, Napierala, Marek, Napierala, Jill S., Ruiz, Luis, Napoli, Eleonora, Perlman, Susan, Giulivi, Cecilia, Cortopassi, Gino A.
Publié dans PLoS One (2019)

Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice

par Tomilov, Alexey A., Bicocca, Vincent, Schoenfeld, Robert A., Giorgio, Marco, Migliaccio, Enrica, Ramsey, Jon J., Hagopian, Kevork, Pelicci, Pier Giuseppe, Cortopassi, Gino A.
Publié 2010

Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model

par Shan, Yuxi, Schoenfeld, Robert A., Hayashi, Genki, Napoli, Eleonora, Akiyama, Tasuku, Iodi Carstens, Mirela, Carstens, Earl E., Pook, Mark A., Cortopassi, Gino A.
Publié 2013

Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system

par Scharadin, Tiffany M., He, Wei, Yiannakou, Yianni, Tomilov, Alexey A., Saldana, Matthew, Cortopassi, Gino A., Carraway, Kermit L., Coleman, Matthew A., Henderson, Paul T.
Publié dans PLoS One (2017)

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia

par Sahdeo, Sunil, Scott, Brian D., McMackin, Marissa Z., Jasoliya, Mittal, Brown, Brandon, Wulff, Heike, Perlman, Susan L., Pook, Mark A., Cortopassi, Gino A.
Publié dans Hum Mol Genet (2014)

Shc Proteins Influence the Activities of Enzymes Involved in Fatty Acid Oxidation and Ketogenesis

par Hagopian, Kevork, Tomilov, Alexey A., Tomilova, Natalia, Kim, Kyoungmi, Taylor, Sandra L., Lam, Adam K., Cortopassi, Gino A., McDonald, Roger B., Ramsey, Jon J.
Publié 2012

The Shc locus regulates insulin signaling and adiposity in mammals

par Tomilov, Alexey A., Ramsey, Jon J., Hagopian, Kevork, Giorgio, Marco, Kim, Kyoungmi M., Lam, Adam, Migliaccio, Enrica, Lloyd, Kent C., Berniakovich, Ina, Prolla, Tomas A., Pelicci, PierGiuseppe, Cortopassi, Gino A.
Publié 2010