Potential biomarker identification for Friedreich’s ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion

Friedreich’s ataxia (FA) is a neurodegenerative disease with no approved therapy that is the result of frataxin deficiency. The identification of human FA blood biomarkers related to disease severity and neuro-pathomechanism could support clinical trials of drug efficacy. To try to identify human bi...

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Veröffentlicht in:PLoS One
Hauptverfasser: McMackin, Marissa Z., Durbin-Johnson, Blythe, Napierala, Marek, Napierala, Jill S., Ruiz, Luis, Napoli, Eleonora, Perlman, Susan, Giulivi, Cecilia, Cortopassi, Gino A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821053/
https://ncbi.nlm.nih.gov/pubmed/31665133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223209
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