Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model

Aims: Oxidative stress is thought to be involved in Friedreich's ataxia (FRDA), yet it has not been demonstrated in the target neurons that are first to degenerate. Using the YG8R mouse model of FRDA, microarray and neuritic growth experiments were carried out in the dorsal root ganglion (DRG),...

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Main Authors: Shan, Yuxi, Schoenfeld, Robert A., Hayashi, Genki, Napoli, Eleonora, Akiyama, Tasuku, Iodi Carstens, Mirela, Carstens, Earl E., Pook, Mark A., Cortopassi, Gino A.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
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Original Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797453/
https://ncbi.nlm.nih.gov/pubmed/23350650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4537
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