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Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model

Aims: Oxidative stress is thought to be involved in Friedreich's ataxia (FRDA), yet it has not been demonstrated in the target neurons that are first to degenerate. Using the YG8R mouse model of FRDA, microarray and neuritic growth experiments were carried out in the dorsal root ganglion (DRG),...

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Bibliografiske detaljer
Main Authors: Shan, Yuxi, Schoenfeld, Robert A., Hayashi, Genki, Napoli, Eleonora, Akiyama, Tasuku, Iodi Carstens, Mirela, Carstens, Earl E., Pook, Mark A., Cortopassi, Gino A.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797453/
https://ncbi.nlm.nih.gov/pubmed/23350650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4537
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