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The Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant Cells
PURPOSE: Benzalkonium chloride (BAK) is the most commonly used eye drop preservative. Benzalkonium chloride has been associated with toxic effects such as “dry eye” and trabecular meshwork degeneration, but the underlying biochemical mechanism of ocular toxicity by BAK is unclear. In this study, we...
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| Опубликовано в: : | Invest Ophthalmol Vis Sci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Association for Research in Vision and Ophthalmology
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407244/ https://ncbi.nlm.nih.gov/pubmed/28444329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20903 |
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