The DNA methylation signature of human TCRαβ+CD4−CD8− double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune...

Por Renauer, Paul A., Coit, Patrick, Sawalha, Amr H.
Publicado no Clin Immunol (2014)

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies

Por Altorok, Nezam, Tsou, Pei-Suen, Coit, Patrick, Khanna, Dinesh, Sawalha, Amr H
Publicado no Ann Rheum Dis (2014)

Epigenome-wide scan identifies a treatment-responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells in Behçet’s disease

Por Hughes, Travis, Ture-Ozdemir, Filiz, Alibaz-Oner, Fatma, Coit, Patrick, Direskeneli, Haner, Sawalha, Amr H
Publicado em 2014

Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity

Por Coit, Patrick, Ognenovski, Mikhail, Gensterblum, Elizabeth, Maksimowicz-McKinnon, Kathleen, Wren, Jonathan D., Sawalha, Amr H.
Publicado no Epigenetics Chromatin (2015)

Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival

Por Kazzaz, Nayef M, Coit, Patrick, Lewis, Emily E, McCune, W Joseph, Sawalha, Amr H, Knight, Jason S
Publicado no Lupus Sci Med (2015)

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

Por Coit, Patrick, Yalavarthi, Srilakshmi, Ognenovski, Mikhail, Zhao, Wenpu, Hasni, Sarfaraz, Wren, Jonathan D., Kaplan, Mariana J., Sawalha, Amr H.
Publicado no J Autoimmun (2015)

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

Por Coit, Patrick, Renauer, Paul, Jeffries, Matlock A., Merrill, Joan T., McCune, W. Joseph, Maksimowicz-McKinnon, Kathleen, Sawalha, Amr H.
Publicado no J Autoimmun (2015)

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus

Por Renauer, Paul, Coit, Patrick, Jeffries, Matlock A, Merrill, Joan T, McCune, W Joseph, Maksimowicz-McKinnon, Kathleen, Sawalha, Amr H
Publicado no Lupus Sci Med (2015)

Epigenetic reprogramming in naïve CD4+ T cells favoring T cell activation and non-Th1 effector T cell immune response as an early event in lupus flares

Por Coit, Patrick, Dozmorov, Mikhail G., Merrill, Joan T., McCune, W. Joseph, Maksimowicz-McKinnon, Kathleen, Wren, Jonathan D., Sawalha, Amr H.
Publicado no Arthritis Rheumatol (2016)

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

Por Coit, Patrick, Jeffries, Matlock, Altorok, Nezam, Dozmorov, Mikhail G., Koelsch, Kristi A., Wren, Jonathan D., Merrill, Joan T., McCune, W. Joseph, Sawalha, Amr H.
Publicado em 2013

Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses

Por Mok, Amanda, Solomon, Olivia, Nayak, Renuka R, Coit, Patrick, Quach, Hong L, Nititham, Joanne, Sawalha, Amr H, Barcellos, Lisa F, Criswell, Lindsey A, Chung, Sharon A
Publicado no Lupus Sci Med (2016)

Genome-wide DNA methylation patterns in naïve CD4(+) T cells from patients with primary Sjögren’s syndrome

Por Altorok, Nezam, Coit, Patrick, Hughes, Travis, Koelsch, Kristi A., Stone, Donald U., Rasmussen, Astrid, Radfar, Lida, Scofield, R. Hal, Sivils, Kathy L., Farris, A. Darise, Sawalha, Amr H.
Publicado em 2014

Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy

Por Carmona, F. David, Coit, Patrick, Saruhan-Direskeneli, Güher, Hernández-Rodríguez, José, Cid, María C., Solans, Roser, Castañeda, Santos, Vaglio, Augusto, Direskeneli, Haner, Merkel, Peter A., Boiardi, Luigi, Salvarani, Carlo, González-Gay, Miguel A., Martín, Javier, Sawalha, Amr H.
Publicado no Sci Rep (2017)

Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy

Por Carmona, F. David, Coit, Patrick, Saruhan-Direskeneli, Güher, Hernández-Rodríguez, José, Cid, María C., Solans, Roser, Castañeda, Santos, Vaglio, Augusto, Direskeneli, Haner, Merkel, Peter A., Boiardi, Luigi, Salvarani, Carlo, González-Gay, Miguel A., Martín, Javier, Sawalha, Amr H.
Publicado no Sci Rep (2017)

Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis

Por Saruhan-Direskeneli, Güher, Hughes, Travis, Aksu, Kenan, Keser, Gokhan, Coit, Patrick, Aydin, Sibel Z., Alibaz-Oner, Fatma, Kamalı, Sevil, Inanc, Murat, Carette, Simon, Hoffman, Gary S., Akar, Servet, Onen, Fatos, Akkoc, Nurullah, Khalidi, Nader A., Koening, Curry, Karadag, Omer, Kiraz, Sedat, Langford, Carol A., McAlear, Carol A., Ozbalkan, Zeynep, Ates, Askin, Karaaslan, Yasar, Maksimowicz-McKinnon, Kathleen, Monach, Paul A., Ozer, Hüseyin T., Seyahi, Emire, Fresko, Izzet, Cefle, Ayse, Seo, Philip, Warrington, Kenneth J., Ozturk, Mehmet A., Ytterberg, Steven R., Cobankara, Veli, Onat, A. Mesut, Guthridge, Joel M., James, Judith A., Tunc, Ercan, Duzgun, Nurşen, Bıcakcıgil, Muge, Yentür, Sibel P., Merkel, Peter A., Direskeneli, Haner, Sawalha, Amr H.
Publicado em 2013

Genome-wide association study identifies susceptibility loci in IL6, RPS9/LILRB3, and an intergenic locus on chromosome 21q22 in Takayasu’s arteritis

Por Renauer, Paul, Saruhan-Direskeneli, Guher, Coit, Patrick, Adler, Adam, Aksu, Kenan, Keser, Gokhan, Alibaz-Oner, Fatma, Aydin, Sibel Z., Kamali, Sevil, Inanc, Murat, Carette, Simon, Cuthbertson, David, Hoffman, Gary S., Akar, Servet, Onen, Fatos, Akkoc, Nurullah, Khalidi, Nader A., Koening, Curry, Karadag, Omer, Kiraz, Sedat, Langford, Carol A., Maksimowicz-McKinnon, Kathleen, McAlear, Carol A., Ozbalkan, Zeynep, Ates, Askin, Karaaslan, Yasar, Duzgun, Nursen, Monach, Paul A., Ozer, Huseyin TE, Erken, Eren, Ozturk, Mehmet A., Yazici, Ayten, Cefle, Ayse, Onat, A. Mesut, Kisacik, Bunyamin, Pagnoux, Christian, Kasifoglu, Timucin, Seyahi, Emire, Fresko, Izzet, Seo, Philip, Sreih, Antoine, Warrington, Kenneth J., Ytterberg, Steven R., Cobankara, Veli, Cunninghame-Graham, Deborah S., Vyse, Timothy J., Pamuk, Omer N., Tunc, Ercan, Dalkilic, Ediz, Bicakcigil, Muge, Yentur, Sibel P., Wren, Jonathan D., Merkel, Peter A., Direskeneli, Haner, Sawalha, Amr H.
Publicado no Arthritis Rheumatol (2015)