Genome-wide DNA methylation patterns in naïve CD4(+) T cells from patients with primary Sjögren’s syndrome

OBJECTIVE: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with incompletely understood etiology. Very little is known about the role of epigenetic dysregulation in the pathogenesis of pSS. METHODS: We performed a genome-wide DNA methylation study in naïve CD4(+) T cells in eleven...

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Autores principales: Altorok, Nezam, Coit, Patrick, Hughes, Travis, Koelsch, Kristi A., Stone, Donald U., Rasmussen, Astrid, Radfar, Lida, Scofield, R. Hal, Sivils, Kathy L., Farris, A. Darise, Sawalha, Amr H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009982/
https://ncbi.nlm.nih.gov/pubmed/24574234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38264
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