Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses

OBJECTIVE: Previous studies have shown that differential DNA methylation is associated with SLE susceptibility. How DNA methylation affects the clinical heterogeneity of SLE has not been fully defined. We conducted this study to identify differentially methylated CpG sites associated with nephritis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lupus Sci Med
Prif Awduron: Mok, Amanda, Solomon, Olivia, Nayak, Renuka R, Coit, Patrick, Quach, Hong L, Nititham, Joanne, Sawalha, Amr H, Barcellos, Lisa F, Criswell, Lindsey A, Chung, Sharon A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2016
Pynciau:
Genetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5174796/
https://ncbi.nlm.nih.gov/pubmed/28074145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2016-000183
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