Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses

OBJECTIVE: Previous studies have shown that differential DNA methylation is associated with SLE susceptibility. How DNA methylation affects the clinical heterogeneity of SLE has not been fully defined. We conducted this study to identify differentially methylated CpG sites associated with nephritis...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Lupus Sci Med
Κύριοι συγγραφείς: Mok, Amanda, Solomon, Olivia, Nayak, Renuka R, Coit, Patrick, Quach, Hong L, Nititham, Joanne, Sawalha, Amr H, Barcellos, Lisa F, Criswell, Lindsey A, Chung, Sharon A
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BMJ Publishing Group 2016
Θέματα:
Genetics
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5174796/
https://ncbi.nlm.nih.gov/pubmed/28074145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2016-000183
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