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Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies

BACKGROUND: The aetiology of systemic sclerosis (SSc) is not clear, but there is an emerging evidence of gene-specific epigenetic dysregulation in the pathogenesis of SSc. METHODS: We performed a genome-wide DNA methylation study in dermal fibroblasts in six diffuse cutaneous SSc (dSSc) patients, si...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Ann Rheum Dis
मुख्य लेखकों: Altorok, Nezam, Tsou, Pei-Suen, Coit, Patrick, Khanna, Dinesh, Sawalha, Amr H
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224992/
https://ncbi.nlm.nih.gov/pubmed/24812288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205303
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