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Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma

OBJECTIVES: We previously identified CYR61 as an HDAC5-repressed gene in scleroderma (SSc) endothelial cells (ECs). When overexpressed, CYR61 promoted angiogenesis in SSc ECs. In this study we examined the role of CYR61 in fibrosis and determined the mechanisms involved in CYR61-mediated angiogenesi...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Tsou, Pei-Suen, Khanna, Dinesh, Sawalha, Amr H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663606/
https://ncbi.nlm.nih.gov/pubmed/30884213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40890
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