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Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma

OBJECTIVES: We previously identified CYR61 as an HDAC5-repressed gene in scleroderma (SSc) endothelial cells (ECs). When overexpressed, CYR61 promoted angiogenesis in SSc ECs. In this study we examined the role of CYR61 in fibrosis and determined the mechanisms involved in CYR61-mediated angiogenesi...

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Dettagli Bibliografici
Pubblicato in:Arthritis Rheumatol
Autori principali: Tsou, Pei-Suen, Khanna, Dinesh, Sawalha, Amr H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663606/
https://ncbi.nlm.nih.gov/pubmed/30884213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40890
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