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Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma

OBJECTIVES: We previously identified CYR61 as an HDAC5-repressed gene in scleroderma (SSc) endothelial cells (ECs). When overexpressed, CYR61 promoted angiogenesis in SSc ECs. In this study we examined the role of CYR61 in fibrosis and determined the mechanisms involved in CYR61-mediated angiogenesi...

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Bibliografske podrobnosti
izdano v:Arthritis Rheumatol
Main Authors: Tsou, Pei-Suen, Khanna, Dinesh, Sawalha, Amr H.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663606/
https://ncbi.nlm.nih.gov/pubmed/30884213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40890
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