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Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts
OBJECTIVE: Emerging evidence supports a role for epigenetic regulation in the pathogenesis of scleroderma (SSc). We aimed to assess the role of methyl-CpG-binding protein 2 (MeCP2), a key epigenetic regulator, in fibroblast activation and fibrosis in SSc. METHODS: Dermal fibroblasts were isolated fr...
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| Publicado no: | Ann Rheum Dis |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7297461/ https://ncbi.nlm.nih.gov/pubmed/29760157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-213022 |
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