Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13

Por Kozasa, Tohru, Hajicek, Nicole, Chow, Christina R., Suzuki, Nobuchika
Publicado em 2011

Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity

Por Chow, Christina R., Suzuki, Nobuchika, Kawamura, Takeshi, Hamakubo, Takao, Kozasa, Tohru
Publicado em 2013

Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα(13) Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling

Por Chow, Christina R., Ebine, Kazumi, Knab, Lawrence M., Bentrem, David J., Kumar, Krishan, Munshi, Hidayatullah G.
Publicado no J Biol Chem (2016)

Interaction of tRNA with MEK2 in pancreatic cancer cells

Por Wang, Xiaoyun, Chow, Christina R., Ebine, Kazumi, Lee, Jiyoung, Rosner, Marsha R., Pan, Tao, Munshi, Hidayatullah G.
Publicado no Sci Rep (2016)

G protein subunit Gα(13) binds to integrin α(IIb)β(3) and mediates integrin “outside-in” signaling

Por Gong, Haixia, Shen, Bo, Flevaris, Panagiotis, Chow, Christina, Lam, Stephen C.-T., Voyno-Yasenetskaya, Tatyana A., Kozasa, Tohru, Du, Xiaoping
Publicado em 2010

Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia

Por Ebine, Kazumi, Chow, Christina R., DeCant, Brian T., Hattaway, Holly Z., Grippo, Paul J., Kumar, Krishan, Munshi, Hidayatullah G.
Publicado no Sci Rep (2016)

BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen

Por Sahai, Vaibhav, Kumar, Krishan, Knab, Lawrence M., Chow, Christina R., Raza, Sania S., Bentrem, David J., Ebine, Kazumi, Munshi, Hidayatullah G.
Publicado em 2014

Identification of Critical Residues in Gα(13) for Stimulation of p115RhoGEF Activity and the Structure of the Gα(13)-p115RhoGEF Regulator of G Protein Signaling Homology (RH) Domai...

Por Hajicek, Nicole, Kukimoto-Niino, Mutsuko, Mishima-Tsumagari, Chiemi, Chow, Christina R., Shirouzu, Mikako, Terada, Takaho, Patel, Maulik, Yokoyama, Shigeyuki, Kozasa, Tohru
Publicado em 2011

Differential Regulation of ZEB1 and EMT by MAPK-interacting protein kinases (MNKs) and eIF4E in Pancreatic Cancer

Por Kumar, Krishan, Chow, Christina R., Ebine, Kazumi, Arslan, Ahmet D., Kwok, Benjamin, Bentrem, David J., Eckerdt, Frank D., Platanias, Leonidas C., Munshi, Hidayatullah G.
Publicado no Mol Cancer Res (2015)

GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1

Por Kumar, Krishan, Raza, Sania S., Knab, Lawrence M., Chow, Christina R., Kwok, Benjamin, Bentrem, David J., Popovic, Relja, Ebine, Kazumi, Licht, Jonathan D., Munshi, Hidayatullah G.
Publicado no Sci Rep (2015)

Snail Cooperates with Kras(G12D) in vivo to Increase Stem Cell Factor and Enhance Mast Cell

Por Knab, Infiltration Lawrence M., Ebine, Kazumi, Chow, Christina R., Raza, Sania S., Sahai, Vaibhav, Patel, Akash P., Kumar, Krishan, Bentrem, David J., Grippo, Paul J., Munshi, Hidayatullah G.
Publicado em 2014