Is the Immune System Impaired in Patients with Severe Acute Respiratory Syndrome?

Por Zhou, Yi-Hua, Chen, Zhaochun
Publicado no Clin Infect Dis (2004)

Monoclonal Antibody Therapies against Anthrax

Por Chen, Zhaochun, Moayeri, Mahtab, Purcell, Robert
Publicado em 2011

Structural basis of anthrax edema factor neutralization by a neutralizing antibody

Por Makiya, Michelle, Dolan, Michael, Agulto, Liane, Purcell, Robert, Chen, Zhaochun
Publicado em 2011

A Single Chimpanzee-Human Neutralizing Monoclonal Antibody Provides Post-exposure Protection Against Type 1 and Type 2 Polioviruses

Por Kouiavskaia, Diana, Chen, Zhaochun, Dragunsky, Eugenia, Mirochnitchenko, Olga, Purcell, Robert, Chumakov, Konstantin
Publicado no J Clin Virol (2015)

Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding

Por Chen, Zhaochun, Moayeri, Mahtab, Zhao, Huaying, Crown, Devorah, Leppla, Stephen H., Purcell, Robert H.
Publicado em 2009

Novel Chimpanzee/Human Monoclonal Antibodies That Neutralize Anthrax Lethal Factor, and Evidence for Possible Synergy with Anti-Protective Antigen Antibody

Por Chen, Zhaochun, Moayeri, Mahtab, Crown, Devorah, Emerson, Suzanne, Gorshkova, Inna, Schuck, Peter, Leppla, Stephen H., Purcell, Robert H.
Publicado em 2009

Chimpanzee-Human Monoclonal Antibodies for Treatment of Chronic Poliovirus Excretors and Emergency Postexposure Prophylaxis

Por Chen, Zhaochun, Chumakov, Konstantin, Dragunsky, Eugenia, Kouiavskaia, Diana, Makiya, Michelle, Neverov, Alexander, Rezapkin, Gennady, Sebrell, Andrew, Purcell, Robert
Publicado em 2011

Development of Norwalk Virus-Specific Monoclonal Antibodies with Therapeutic Potential for the Treatment of Norwalk Virus Gastroenteritis

Por Chen, Zhaochun, Sosnovtsev, Stanislav V., Bok, Karin, Parra, Gabriel I., Makiya, Michelle, Agulto, Liane, Green, Kim Y., Purcell, Robert H.
Publicado em 2013

Bacillus anthracis Capsular Conjugates Elicit Chimpanzee Polyclonal Antibodies That Protect Mice from Pulmonary Anthrax

Por Chen, Zhaochun, Schneerson, Rachel, Lovchik, Julie A., Dai, Zhongdong, Kubler-Kielb, Joanna, Agulto, Liane, Leppla, Stephen H., Purcell, Robert H.
Publicado no Clin Vaccine Immunol (2015)

Distinct Cytokine Profiles Correlate with Disease Severity and Outcome in Longitudinal Studies of Acute Hepatitis B Virus and Hepatitis D Virus Infection in Chimpanzees

Por Engle, Ronald E., De Battista, Davide, Danoff, Emily J., Nguyen, Hanh, Chen, Zhaochun, Lusso, Paolo, Purcell, Robert H., Farci, Patrizia
Publicado no mBio (2020)

Detection of Anthrax Toxin by an Ultrasensitive Immunoassay Using Europium Nanoparticles

Por Tang, Shixing, Moayeri, Mahtab, Chen, Zhaochun, Harma, Harri, Zhao, Jiangqin, Hu, Haijing, Purcell, Robert H., Leppla, Stephen H., Hewlett, Indira K.
Publicado em 2009

Rapid discovery and characterization of synthetic neutralizing antibodies against anthrax edema toxin

Por Farcasanu, Mara, Wang, Andrew G., Uchański, Tomasz, Bailey, Lucas J., Yue, Jiping, Chen, Zhaochun, Wu, Xiaoyang, Kossiakoff, Anthony, Tang, Wei-Jen
Publicado no Biochemistry (2019)

Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule

Por Chen, Zhaochun, Schneerson, Rachel, Lovchik, Julie, Lyons, C. Rick, Zhao, Huaying, Dai, Zhongdong, Kubler-Kielb, Joanna, Leppla, Stephen H., Purcell, Robert H.
Publicado em 2011

Specificity of an Anti-Capsid Antibody Associated with Hepatitis B Virus-Related Acute Liver Failure

Por Wu, Weimin, Chen, Zhaochun, Cheng, Naiqian, Watts, Norman R., Stahl, Stephen J., Farci, Patrizia, Purcell, Robert H., Wingfield, Paul T., Steven, Alasdair C.
Publicado em 2012

Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

Por Leysath, Clinton E., Chen, Kuang-Hua, Moayeri, Mahtab, Crown, Devorah, Fattah, Rasem, Chen, Zhaochun, Das, Suman R., Purcell, Robert H., Leppla, Stephen H.
Publicado em 2011

Cross-neutralizing human anti-poliovirus antibodies bind the recognition site for cellular receptor

Por Chen, Zhaochun, Fischer, Elizabeth R., Kouiavskaia, Diana, Hansen, Bryan T., Ludtke, Steven J., Bidzhieva, Bella, Makiya, Michelle, Agulto, Liane, Purcell, Robert H., Chumakov, Konstantin
Publicado em 2013

Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and...

Por Altaweel, Laith, Chen, Zhaochun, Moayeri, Mahtab, Cui, Xizhong, Li, Yan, Su, Junwu, Fitz, Yvonne, Johnson, Syd, Leppla, Stephen H., Purcell, Robert, Eichacker, Peter Q.
Publicado em 2011

Efficient Neutralization of Anthrax Toxin by Chimpanzee Monoclonal Antibodies against Protective Antigen

Por Chen, Zhaochun, Moayeri, Mahtab, Zhou, Yi-Hua, Leppla, Stephen, Emerson, Suzanne, Sebrell, Andrew, Yu, Fujuan, Svitel, Juraj, Schuck, Peter, St. Claire, Marisa, Purcell, Robert
Publicado no J Infect Dis (2006)

B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus–associated acute liver failure

Por Farci, Patrizia, Diaz, Giacomo, Chen, Zhaochun, Govindarajan, Sugantha, Tice, Ashley, Agulto, Liane, Pittaluga, Stefania, Boon, Denali, Yu, Claro, Engle, Ronald E., Haas, Mark, Simon, Richard, Purcell, Robert H., Zamboni, Fausto
Publicado em 2010

Characterization of Chimpanzee/Human Monoclonal Antibodies to Vaccinia Virus A33 Glycoprotein and Its Variola Virus Homolog In Vitro and in a Vaccinia Virus Mouse Protection Model

Por Chen, Zhaochun, Earl, Patricia, Americo, Jeffrey, Damon, Inger, Smith, Scott K., Yu, Fujuan, Sebrell, Andrew, Emerson, Suzanne, Cohen, Gary, Eisenberg, Roselyn J., Gorshkova, Inna, Schuck, Peter, Satterfield, William, Moss, Bernard, Purcell, Robert
Publicado em 2007