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Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

Bacillus anthracis is the causative agent of anthrax, and the tripartite anthrax toxin is an essential element of its pathogenesis. Edema factor (EF), a potent adenylyl cyclase, is one of the toxin components. In this work, anti-EF monoclonal antibodies (MAb) were produced following immunization of...

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Bibliographic Details
Main Authors: Leysath, Clinton E., Chen, Kuang-Hua, Moayeri, Mahtab, Crown, Devorah, Fattah, Rasem, Chen, Zhaochun, Das, Suman R., Purcell, Robert H., Leppla, Stephen H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257937/
https://ncbi.nlm.nih.gov/pubmed/21911463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05314-11
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