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Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

Bacillus anthracis is the causative agent of anthrax, and the tripartite anthrax toxin is an essential element of its pathogenesis. Edema factor (EF), a potent adenylyl cyclase, is one of the toxin components. In this work, anti-EF monoclonal antibodies (MAb) were produced following immunization of...

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Autors principals: Leysath, Clinton E., Chen, Kuang-Hua, Moayeri, Mahtab, Crown, Devorah, Fattah, Rasem, Chen, Zhaochun, Das, Suman R., Purcell, Robert H., Leppla, Stephen H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257937/
https://ncbi.nlm.nih.gov/pubmed/21911463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05314-11
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