Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

Bacillus anthracis is the causative agent of anthrax, and the tripartite anthrax toxin is an essential element of its pathogenesis. Edema factor (EF), a potent adenylyl cyclase, is one of the toxin components. In this work, anti-EF monoclonal antibodies (MAb) were produced following immunization of...

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Hlavní autoři: Leysath, Clinton E., Chen, Kuang-Hua, Moayeri, Mahtab, Crown, Devorah, Fattah, Rasem, Chen, Zhaochun, Das, Suman R., Purcell, Robert H., Leppla, Stephen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257937/
https://ncbi.nlm.nih.gov/pubmed/21911463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05314-11
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