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Role of N-Terminal Amino Acids in the Potency of Anthrax Lethal Factor
Anthrax lethal factor (LF) is a Zn(+2)-dependent metalloprotease that cleaves several MAPK kinases and is responsible for the lethality of anthrax lethal toxin (LT). We observed that a recombinant LF (LF-HMA) which differs from wild type LF (LF-A) by the addition of two residues (His-Met) to the nat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518864/ https://ncbi.nlm.nih.gov/pubmed/18769623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003130 |
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