Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

Bacillus anthracis is the causative agent of anthrax, and the tripartite anthrax toxin is an essential element of its pathogenesis. Edema factor (EF), a potent adenylyl cyclase, is one of the toxin components. In this work, anti-EF monoclonal antibodies (MAb) were produced following immunization of...

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Main Authors: Leysath, Clinton E., Chen, Kuang-Hua, Moayeri, Mahtab, Crown, Devorah, Fattah, Rasem, Chen, Zhaochun, Das, Suman R., Purcell, Robert H., Leppla, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257937/
https://ncbi.nlm.nih.gov/pubmed/21911463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05314-11
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