Methionine Oxidation in the Calmodulin-Binding Domain of Calcineurin Disrupts Calmodulin Binding and Calcineurin Activation

Por Carruthers, Nicholas J., Stemmer, Paul M.
Publicado em 2008

Classification-Based Quantitative Analysis of Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) Data

Por Kim, Seongho, Carruthers, Nicholas, Lee, Joohyoung, Chinni, Sreenivasa, Stemmer, Paul
Publicado no Comput Methods Programs Biomed (2016)

Protein Mobility Shifts Contribute to Gel Electrophoresis Liquid Chromatography Analysis

Por Carruthers, Nicholas J., Parker, Graham C., Gratsch, Theresa, Caruso, Joseph A., Stemmer, Paul M.
Publicado no J Biomol Tech (2015)

Proteomic profile of Embryonic Stem Cells with low Survival Motor Neuron protein is consistent with developmental dysfunction

Por Parker, Graham C., Carruthers, Nicholas J., Gratsch, Theresa, Caruso, Joseph A., Stemmer, Paul M.
Publicado no J Neural Transm (Vienna) (2016)

Mercury Alters B-Cell Protein Phosphorylation Profiles

Por Carruthers, Nicholas J., Stemmer, Paul M., Shin, Namhee, Dombkowski, Alan, Caruso, Joseph A., Gill, Randal, Rosenspire, Allen
Publicado em 2013

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects

Por Dvorak, Curt A., Liu, Changlu, Shelton, Jonathan, Kuei, Chester, Sutton, Steven W., Lovenberg, Timothy W., Carruthers, Nicholas I.
Publicado em 2012

Synthesis, SAR, and Pharmacological Characterization of Brain Penetrant P2X7 Receptor Antagonists

Por Savall, Brad M., Wu, Duncan, De Angelis, Meri, Carruthers, Nicholas I., Ao, Hong, Wang, Qi, Lord, Brian, Bhattacharya, Anindya, Letavic, Michael A.
Publicado no ACS Med Chem Lett (2015)

Cortical Tubers: Windows into Dysregulation of Epilepsy Risk and Synaptic Signaling Genes by MicroRNAs

Por Dombkowski, Alan A., Batista, Carlos E., Cukovic, Daniela, Carruthers, Nicholas J., Ranganathan, Ramya, Shukla, Upasana, Stemmer, Paul M., Chugani, Harry T., Chugani, Diane C.
Publicado no Cereb Cortex (2016)

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [(11)C]GSK189254 in anesthetized baboon

Por Logan, Jean, Carruthers, Nicholas I., Letavic, Michael A., Sands, Steven, Jiang, Xiaohui, Shea, Colleen, Muench, Lisa, Xu, Youwen, Carter, Pauline, King, Payton, Fowler, Joanna S.
Publicado em 2012

Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor

Por Dvorak, Curt A., Coate, Heather, Nepomuceno, Diane, Wennerholm, Michelle, Kuei, Chester, Lord, Brian, Woody, David, Bonaventure, Pascal, Liu, Changlu, Lovenberg, Timothy, Carruthers, Nicholas I.
Publicado no ACS Med Chem Lett (2015)

Proteomic Characterization of Phagosomal Membrane Microdomains During Phagolysosome Biogenesis and Evolution

Por Goyette, Guillaume, Boulais, Jonathan, Carruthers, Nicholas J., Landry, Christian R., Jutras, Isabelle, Duclos, Sophie, Dermine, Jean-François, Michnick, Stephen W., LaBoissière, Sylvie, Lajoie, Gilles, Barreiro, Luis, Thibault, Pierre, Desjardins, Michel
Publicado em 2012

A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects

Por Bonaventure, Pascal, Yun, Sujin, Johnson, Philip L., Shekhar, Anantha, Fitz, Stephanie D., Shireman, Brock T., Lebold, Terry P., Nepomuceno, Diane, Lord, Brian, Wennerholm, Michelle, Shelton, Jonathan, Carruthers, Nicholas, Lovenberg, Timothy, Dugovic, Christine
Publicado no J Pharmacol Exp Ther (2015)

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X(7) Antagonists

Por Letavic, Michael A., Lord, Brian, Bischoff, Francois, Hawryluk, Natalie A., Pieters, Serge, Rech, Jason C., Sales, Zachary, Velter, Adriana I., Ao, Hong, Bonaventure, Pascal, Contreras, Victor, Jiang, Xiaohui, Morton, Kirsten L., Scott, Brian, Wang, Qi, Wickenden, Alan D., Carruthers, Nicholas I., Bhattacharya, Anindya
Publicado em 2013

Novel Benzamide-Based Histamine H3 Receptor Antagonists: The Identification of Two Candidates for Clinical Development

Por Letavic, Michael A., Aluisio, Leah, Apodaca, Richard, Bajpai, Manoj, Barbier, Ann J., Bonneville, Anne, Bonaventure, Pascal, Carruthers, Nicholas I., Dugovic, Christine, Fraser, Ian C., Kramer, Michelle L., Lord, Brian, Lovenberg, Timothy W., Li, Lilian Y., Ly, Kiev S., Mcallister, Heather, Mani, Neelakandha S., Morton, Kirsten L., Ndifor, Anthony, Nepomuceno, S. Diane, Pandit, Chennagiri R., Sands, Steven B., Shah, Chandra R., Shelton, Jonathan E., Snook, Sandra S., Swanson, Devin M., Xiao, Wei
Publicado no ACS Med Chem Lett (2015)