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Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects
[Image: see text] Following the characterization of the lactate receptor (GPR81), a focused screening effort afforded 3-hydroxybenzoic acid 1 as a weak agonist of both GPR81 and GPR109a (niacin receptor). An examination of structurally similar arylhydroxy acids led to the identification of 3-chloro-...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American
Chemical Society
2012
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025785/ https://ncbi.nlm.nih.gov/pubmed/24900524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml3000676 |
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