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Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro
It is now well established that GPR139, a G-protein coupled receptor exclusively expressed in the brain and pituitary, is activated by the essential amino acids L-tryptophan (L-Trp) and L-phenylalanine (L-Phe) via G(αq)-coupling. The in vitro affinity and potency values of L-Trp and L-Phe are within...
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| Yayımlandı: | Front Pharmacol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5863515/ https://ncbi.nlm.nih.gov/pubmed/29599718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00157 |
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