GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact

GPR139, a G(q)-coupled receptor that is activated by the essential amino acids L-tryptophan and L-phenylalanine, is predominantly expressed in the brain and pituitary. The physiological function of GPR139 remains elusive despite the availability of pharmacological tool agonist compounds and knock-ou...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Wang, Lien, Lee, Grace, Kuei, Chester, Yao, Xiang, Harrington, Anthony, Bonaventure, Pascal, Lovenberg, Timothy W., Liu, Changlu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443882/
https://ncbi.nlm.nih.gov/pubmed/30971885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00281
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