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Proteomic profile of Embryonic Stem Cells with low Survival Motor Neuron protein is consistent with developmental dysfunction

Spinal muscular atrophy is an autosomal recessive motor neuron disease caused by a genetic defect carried by as many as one in 75 people. Unlike most neurological disorders, we know exactly what the genetic basis is of the disorder, but in spite of this, have little understanding of why the low leve...

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Библиографические подробности
Опубликовано в: :J Neural Transm (Vienna)
Главные авторы: Parker, Graham C., Carruthers, Nicholas J., Gratsch, Theresa, Caruso, Joseph A., Stemmer, Paul M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097705/
https://ncbi.nlm.nih.gov/pubmed/27145767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-016-1520-y
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