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Proteomic profile of Embryonic Stem Cells with low Survival Motor Neuron protein is consistent with developmental dysfunction

Spinal muscular atrophy is an autosomal recessive motor neuron disease caused by a genetic defect carried by as many as one in 75 people. Unlike most neurological disorders, we know exactly what the genetic basis is of the disorder, but in spite of this, have little understanding of why the low leve...

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Detalhes bibliográficos
Publicado no:J Neural Transm (Vienna)
Main Authors: Parker, Graham C., Carruthers, Nicholas J., Gratsch, Theresa, Caruso, Joseph A., Stemmer, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097705/
https://ncbi.nlm.nih.gov/pubmed/27145767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-016-1520-y
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