Chromatin and Genomic determinants of alternative splicing

Por Wang, Kun, Cao, Kan, Hannenhalli, Sridhar
Publicado no ACM BCB (2015)

Progeria: Translational insights from cell biology

Por Gordon, Leslie B., Cao, Kan, Collins, Francis S.
Publicado em 2012

Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1

Por Zhang, Haoyue, Xiong, Zheng-Mei, Cao, Kan
Publicado em 2014

Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: Implications for normal aging and age-dependent neurodegenerative disorders

Por Graziotto, John J, Cao, Kan, Collins, Francis S, Krainc, Dimitri
Publicado em 2012

Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Por Wu, Di, Yates, Phillip A., Zhang, Haoyue, Cao, Kan
Publicado no Nucleus (2016)

A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells

Por Atchison, Leigh, Zhang, Haoyue, Cao, Kan, Truskey, George A.
Publicado no Sci Rep (2017)

An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells

Por Xiong, Zheng-Mei, LaDana, Christina, Wu, Di, Cao, Kan
Publicado em 2013

Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targeting

Por Wu, Di, Flannery, Andrew R, Cai, Helen, Ko, Eunae, Cao, Kan
Publicado em 2014

Phenotype-Dependent Coexpression Gene Clusters: Application to Normal and Premature Ageing

Por Wang, Kun, Das, Avinash, Xiong, Zheng-Mei, Cao, Kan, Hannenhalli, Sridhar
Publicado no IEEE/ACM Trans Comput Biol Bioinform (2015)

A lamin A protein isoform overexpressed in Hutchinson–Gilford progeria syndrome interferes with mitosis in progeria and normal cells

Por Cao, Kan, Capell, Brian C., Erdos, Michael R., Djabali, Karima, Collins, Francis S.
Publicado em 2007

Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome

Por Zhang, Haoyue, Sun, Linlin, Wang, Kun, Wu, Di, Trappio, Mason, Witting, Celeste, Cao, Kan
Publicado no PLoS One (2016)

Automated image analysis of nuclear shape: What can we learn from a prematurely aged cell?

Por Driscoll, Meghan K., Albanese, Jason L., Xiong, Zheng-Mei, Mailman, Mitch, Losert, Wolfgang, Cao, Kan
Publicado em 2012

Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

Por Xiong, Zheng-Mei, O’Donovan, Mike, Sun, Linlin, Choi, Ji Young, Ren, Margaret, Cao, Kan
Publicado no Sci Rep (2017)

Characterization and Reconstitution of Drosophila γ-Tubulin Ring Complex Subunits

Por Gunawardane, Ruwanthi N., Martin, Ona C., Cao, Kan, Zhang, Lijun, Dej, Kimberly, Iwamatsu, Akihiro, Zheng, Yixian
Publicado em 2000

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

Por Cao, Kan, Blair, Cecilia D., Faddah, Dina A., Kieckhaefer, Julia E., Olive, Michelle, Erdos, Michael R., Nabel, Elizabeth G., Collins, Francis S.
Publicado em 2011

Correlated alterations in genome organization, histone methylation, and DNA–lamin A/C interactions in Hutchinson-Gilford progeria syndrome

Por McCord, Rachel Patton, Nazario-Toole, Ashley, Zhang, Haoyue, Chines, Peter S., Zhan, Ye, Erdos, Michael R., Collins, Francis S., Dekker, Job, Cao, Kan
Publicado em 2013

Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria

Por Xiong, Zheng‐Mei, Choi, Ji Young, Wang, Kun, Zhang, Haoyue, Tariq, Zeshan, Wu, Di, Ko, Eunae, LaDana, Christina, Sesaki, Hiromi, Cao, Kan
Publicado no Aging Cell (2015)

Lamin A and microtubules collaborate to maintain nuclear morphology

Por Tariq, Zeshan, Zhang, Haoyue, Chia-Liu, Alexander, Shen, Yang, Gete, Yantenew, Xiong, Zheng-Mei, Tocheny, Claire, Campanello, Leonard, Wu, Di, Losert, Wolfgang, Cao, Kan
Publicado no Nucleus (2017)

From Cellular Characteristics to Disease Diagnosis: Uncovering Phenotypes with Supercells

Por Candia, Julián, Maunu, Ryan, Driscoll, Meghan, Biancotto, Angélique, Dagur, Pradeep, McCoy, J. Philip, Sen, H. Nida, Wei, Lai, Maritan, Amos, Cao, Kan, Nussenblatt, Robert B., Banavar, Jayanth R., Losert, Wolfgang
Publicado em 2013

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

Por Capell, Brian C., Olive, Michelle, Erdos, Michael R., Cao, Kan, Faddah, Dina A., Tavarez, Urraca L., Conneely, Karen N., Qu, Xuan, San, Hong, Ganesh, Santhi K., Chen, Xiaoyan, Avallone, Hedwig, Kolodgie, Frank D., Virmani, Renu, Nabel, Elizabeth G., Collins, Francis S.
Publicado em 2008