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Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: Implications for normal aging and age-dependent neurodegenerative disorders

While rapamycin has been in use for years in transplant patients as an antirejection drug, more recently it has shown promise in treating diseases of aging, such as neurodegenerative disorders and atherosclerosis. We recently reported that rapamycin reverses the cellular phenotype of fibroblasts fro...

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Détails bibliographiques
Auteurs principaux: Graziotto, John J, Cao, Kan, Collins, Francis S, Krainc, Dimitri
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336000/
https://ncbi.nlm.nih.gov/pubmed/22170152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.8.1.18331
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