Peroxisomal abnormalities and catalase deficiency in Hutchinson-Gilford Progeria Syndrome

Peroxisomes are small, membrane-enclosed eukaryotic organelles that house various enzymes with metabolic functions. One important feature in both Hutchinson-Gilford Progeria Syndrome (HGPS) and normal aging is the elevated levels of Reactive Oxygen Species (ROS), which are generated from metabolic p...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Mao, Xiaojing, Bharti, Pratima, Thaivalappil, Abhirami, Cao, Kan
Format: Artigo
Language:Inglês
Published: Impact Journals 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138560/
https://ncbi.nlm.nih.gov/pubmed/32186522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102941
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