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Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Nuclear lamins are the major components of the nuclear lamina at the periphery of the nucleus, supporting the nuclear envelope and participating in many nuclear processes, including DNA replication, transcription and chromatin organization. A group of diseases, the laminopathies, is associated with...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Wu, Di, Yates, Phillip A., Zhang, Haoyue, Cao, Kan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214577/
https://ncbi.nlm.nih.gov/pubmed/27929926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1260803
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