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Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Nuclear lamins are the major components of the nuclear lamina at the periphery of the nucleus, supporting the nuclear envelope and participating in many nuclear processes, including DNA replication, transcription and chromatin organization. A group of diseases, the laminopathies, is associated with...

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Vydáno v:Nucleus
Hlavní autoři: Wu, Di, Yates, Phillip A., Zhang, Haoyue, Cao, Kan
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214577/
https://ncbi.nlm.nih.gov/pubmed/27929926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1260803
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