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Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Nuclear lamins are the major components of the nuclear lamina at the periphery of the nucleus, supporting the nuclear envelope and participating in many nuclear processes, including DNA replication, transcription and chromatin organization. A group of diseases, the laminopathies, is associated with...

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Publicado en:Nucleus
Main Authors: Wu, Di, Yates, Phillip A., Zhang, Haoyue, Cao, Kan
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214577/
https://ncbi.nlm.nih.gov/pubmed/27929926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1260803
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