A Prototypical Small-Molecule Modulator Uncouples Mitochondria in Response to Endogenous Hydrogen Peroxide Production

nork McQuaker, Stephen J, Quinlan, Casey L, Caldwell, Stuart T, Brand, Martin D, Hartley, Richard C
Argitaratua 2013

Synthesis of an azido-tagged low affinity ratiometric calcium sensor

nork Caldwell, Stuart T., Cairns, Andrew G., Olson, Marnie, Chalmers, Susan, Sandison, Mairi, Mullen, William, McCarron, John G., Hartley, Richard C.
Argitaratua izan da Tetrahedron (2015)

Photoactivated release of membrane impermeant sulfonates inside cells

nork Caldwell, Stuart T., O'Byrne, Sean N., Wilson, Calum, Cvetko, Filip, Murphy, Michael P., McCarron, John G., Hartley, Richard C.
Argitaratua izan da Chem Commun (Camb) (2021)

A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo

nork Burger, Nils, Logan, Angela, Prime, Tracy A., Mottahedin, Amin, Caldwell, Stuart T., Krieg, Thomas, Hartley, Richard C., James, Andrew M., Murphy, Michael P.
Argitaratua izan da Free Radic Biol Med (2020)

Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production

nork Cvetko, Filip, Caldwell, Stuart T., Higgins, Maureen, Suzuki, Takafumi, Yamamoto, Masayuki, Prag, Hiran A., Hartley, Richard C., Dinkova-Kostova, Albena T., Murphy, Michael P.
Argitaratua izan da J Biol Chem (2020)

Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase

nork Cao, Zhenbo, Mitchell, Lorna, Hsia, Oliver, Scarpa, Miriam, Caldwell, Stuart T., Alfred, Arina D., Gennaris, Alexandra, Collet, Jean-François, Hartley, Richard C., Bulleid, Neil J.
Argitaratua izan da Biochem J (2018)

Selective Uncoupling of Individual Mitochondria within a Cell Using a Mitochondria-Targeted Photoactivated Protonophore

nork Chalmers, Susan, Caldwell, Stuart T., Quin, Caroline, Prime, Tracy A., James, Andrew M., Cairns, Andrew G., Murphy, Michael P., McCarron, John G., Hartley, Richard C.
Argitaratua 2011

Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation

nork Pala, Laura, Senn, Hans M., Caldwell, Stuart T., Prime, Tracy A., Warrington, Stefan, Bright, Thomas P., Prag, Hiran A., Wilson, Claire, Murphy, Michael P., Hartley, Richard C.
Argitaratua izan da Front Chem (2020)

Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker

nork Prag, Hiran A., Kula-Alwar, Duvaraka, Pala, Laura, Caldwell, Stuart T., Beach, Timothy E., James, Andrew M., Saeb-Parsy, Kourosh, Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Argitaratua izan da Mol Pharm (2020)

Tetra-arylborate lipophilic anions as targeting groups

nork Gaddale Devanna, Kishore K., Gawel, Justyna M., Prime, Tracy A., Cvetko, Filip, Benincá, Cristiane, Caldwell, Stuart T., Negoda, Alexander, Harrison, Andrew, James, Andrew M., Pavlov, Evgeny V., Murphy, Michael P., Hartley, Richard C.
Argitaratua izan da Chem Commun (Camb) (2021)

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

nork Fazakerley, Daniel J., Minard, Annabel Y., Krycer, James R., Thomas, Kristen C., Stöckli, Jacqueline, Harney, Dylan. J., Burchfield, James G., Maghzal, Ghassan J., Caldwell, Stuart T., Hartley, Richard C., Stocker, Roland, Murphy, Michael P., James, David E.
Argitaratua izan da J Biol Chem (2018)

Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis

nork Antonucci, Salvatore, Mulvey, John F., Burger, Nils, Di Sante, Moises, Hall, Andrew R., Hinchy, Elizabeth C., Caldwell, Stuart T., Gruszczyk, Anja V., Deshwal, Soni, Hartley, Richard C., Kaludercic, Nina, Murphy, Michael P., Di Lisa, Fabio, Krieg, Thomas
Argitaratua izan da Free Radic Biol Med (2019)

The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart

nork Tate, Mitchel, Higgins, Gavin C., De Blasio, Miles J., Lindblom, Runa, Prakoso, Darnel, Deo, Minh, Kiriazis, Helen, Park, Min, Baeza-Garza, Carlos D., Caldwell, Stuart T., Hartley, Richard C., Krieg, Thomas, Murphy, Michael P., Coughlan, Melinda T., Ritchie, Rebecca H.
Argitaratua izan da Cardiovasc Drugs Ther (2019)

Correction to: The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart

nork Tate, Mitchel, Higgins, Gavin C., De Blasio, Miles J., Lindblom, Runa, Prakoso, Darnel, Deo, Minh, Kiriazis, Helen, Park, Min, Baeza-Garza, Carlos D., Caldwell, Stuart T., Hartley, Richard C., Krieg, Thomas, Murphy, Michael P., Coughlan, Melinda T., Ritchie, Rebecca H.
Argitaratua izan da Cardiovasc Drugs Ther (2020)

Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo

nork Booty, Lee M., Gawel, Justyna M., Cvetko, Filip, Caldwell, Stuart T., Hall, Andrew R., Mulvey, John F., James, Andrew M., Hinchy, Elizabeth C., Prime, Tracy A., Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P., Clatworthy, Menna R., Ferdinand, John R., Prag, Hiran A., Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Argitaratua izan da Cell Chem Biol (2019)

MitoNeoD: A Mitochondria-Targeted Superoxide Probe

nork Shchepinova, Maria M., Cairns, Andrew G., Prime, Tracy A., Logan, Angela, James, Andrew M., Hall, Andrew R., Vidoni, Sara, Arndt, Sabine, Caldwell, Stuart T., Prag, Hiran A., Pell, Victoria R., Krieg, Thomas, Mulvey, John F., Yadav, Pooja, Cobley, James N., Bright, Thomas P., Senn, Hans M., Anderson, Robert F., Murphy, Michael P., Hartley, Richard C.
Argitaratua izan da Cell Chem Biol (2017)

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

nork Martin, Jack L., Costa, Ana S. H., Gruszczyk, Anja V., Beach, Timothy E., Allen, Fay M., Prag, Hiran A., Hinchy, Elizabeth C., Mahbubani, Krishnaa, Hamed, Mazin, Tronci, Laura, Nikitopoulou, Efterpi, James, Andrew M., Krieg, Thomas, Robinson, Alan J., Huang, Margaret H., Caldwell, Stuart T., Logan, Angela, Pala, Laura, Hartley, Richard C., Frezza, Christian, Saeb-Parsy, Kourosh, Murphy, Michael P.
Argitaratua izan da Nat Metab (2019)

Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart

nork Park, Min, Nishimura, Takanori, Baeza-Garza, Carlos D., Caldwell, Stuart T., Pun, Pamela Boon Li, Prag, Hiran A., Young, Tim, Sauchanka, Olga, Logan, Angela, Forkink, Marleen, Gruszczyk, Anja V., Prime, Tracy A., Arndt, Sabine, Naudi, Alba, Pamplona, Reinald, Coughlan, Melinda T., Tate, Mitchel, Ritchie, Rebecca H., Caicci, Federico, Kaludercic, Nina, Di Lisa, Fabio, Smith, Robin A. J., Hartley, Richard C., Murphy, Michael P., Krieg, Thomas
Argitaratua izan da Cardiovasc Drugs Ther (2020)

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

nork Mills, Evanna L., Ryan, Dylan G., Prag, Hiran A., Dikovskaya, Dina, Menon, Deepthi, Zaslona, Zbigniew, Jedrychowski, Mark P., Costa, Ana S. H., Higgins, Maureen, Hams, Emily, Szpyt, John, Runtsch, Marah C., King, Martin S., McGouran, Joanna F., Fischer, Roman, Kessler, Benedikt M., McGettrick, Anne F., Hughes, Mark M., Carroll, Richard G., Booty, Lee M., Knatko, Elena V., Meakin, Paul J., Ashford, Michael L. J., Modis, Louise K., Brunori, Gino, Sévin, Daniel C., Fallon, Padraic G., Caldwell, Stuart T., Kunji, Edmund R. S., Chouchani, Edward T., Frezza, Christian, Dinkova-Kostova, Albena T., Hartley, Richard C., Murphy, Michael P., O’Neill, Luke A.
Argitaratua izan da Nature (2018)