Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation

There is considerable interest in developing drugs and probes targeted to mitochondria in order to understand and treat the many pathologies associated with mitochondrial dysfunction. The large membrane potential, negative inside, across the mitochondrial inner membrane enables delivery of molecules...

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Bibliografski detalji
Izdano u:Front Chem
Glavni autori: Pala, Laura, Senn, Hans M., Caldwell, Stuart T., Prime, Tracy A., Warrington, Stefan, Bright, Thomas P., Prag, Hiran A., Wilson, Claire, Murphy, Michael P., Hartley, Richard C.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Chemistry
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509049/
https://ncbi.nlm.nih.gov/pubmed/33033715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00783
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