Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

Mitochondrial oxidative stress, mitochondrial dysfunction, or both have been implicated in insulin resistance. However, disentangling the individual roles of these processes in insulin resistance has been difficult because they often occur in tandem, and tools that selectively increase oxidant produ...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fazakerley, Daniel J., Minard, Annabel Y., Krycer, James R., Thomas, Kristen C., Stöckli, Jacqueline, Harney, Dylan. J., Burchfield, James G., Maghzal, Ghassan J., Caldwell, Stuart T., Hartley, Richard C., Stocker, Roland, Murphy, Michael P., James, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950018/
https://ncbi.nlm.nih.gov/pubmed/29599292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001254
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