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Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes
The Ser/Thr protein kinase Akt regulates essential biological processes such as cell survival, growth, and metabolism. Upon growth factor stimulation, Akt is phosphorylated at Ser(474); however, how this phosphorylation contributes to Akt activation remains controversial. Previous studies, which ind...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851323/ https://ncbi.nlm.nih.gov/pubmed/31548312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010036 |
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