Selective Uncoupling of Individual Mitochondria within a Cell Using a Mitochondria-Targeted Photoactivated Protonophore

[Image: see text] Depolarization of an individual mitochondrion or small clusters of mitochondria within cells has been achieved using a photoactivatable probe. The probe is targeted to the matrix of the mitochondrion by an alkyltriphenylphosphonium lipophilic cation and releases the protonophore 2,...

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Bibliografiske detaljer
Main Authors: Chalmers, Susan, Caldwell, Stuart T., Quin, Caroline, Prime, Tracy A., James, Andrew M., Cairns, Andrew G., Murphy, Michael P., McCarron, John G., Hartley, Richard C.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260739/
https://ncbi.nlm.nih.gov/pubmed/22239373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2077922
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