Tetra-arylborate lipophilic anions as targeting groups

Tetraphenylborate (TPB) anions traverse membranes but are excluded from mitochondria by the membrane potential (Δψ). TPB-conjugates also distributed across membranes in response to Δψ, but surprisingly, they rapidly entered cells. They accumulated within lysosomes following endocystosis. This pH-ind...

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Vydáno v:Chem Commun (Camb)
Hlavní autoři: Gaddale Devanna, Kishore K., Gawel, Justyna M., Prime, Tracy A., Cvetko, Filip, Benincá, Cristiane, Caldwell, Stuart T., Negoda, Alexander, Harrison, Andrew, James, Andrew M., Pavlov, Evgeny V., Murphy, Michael P., Hartley, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2021
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062962/
https://ncbi.nlm.nih.gov/pubmed/33634803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc07924c
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