Tetra-arylborate lipophilic anions as targeting groups

Tetraphenylborate (TPB) anions traverse membranes but are excluded from mitochondria by the membrane potential (Δψ). TPB-conjugates also distributed across membranes in response to Δψ, but surprisingly, they rapidly entered cells. They accumulated within lysosomes following endocystosis. This pH-ind...

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Dettagli Bibliografici
Pubblicato in:Chem Commun (Camb)
Autori principali: Gaddale Devanna, Kishore K., Gawel, Justyna M., Prime, Tracy A., Cvetko, Filip, Benincá, Cristiane, Caldwell, Stuart T., Negoda, Alexander, Harrison, Andrew, James, Andrew M., Pavlov, Evgeny V., Murphy, Michael P., Hartley, Richard C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2021
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062962/
https://ncbi.nlm.nih.gov/pubmed/33634803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc07924c
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