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Accumulation of lipophilic dications by mitochondria and cells

Lipophilic monocations can pass through phospholipid bilayers and accumulate in negatively-charged compartments such as the mitochondrial matrix, driven by the membrane potential. This property is used to visualize mitochondria, to deliver therapeutic molecules to mitochondria and to measure the mem...

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Detalhes bibliográficos
Main Authors: Ross, Meredith F., Da Ros, Tatiana, Blaikie, Frances H., Prime, Tracy A., Porteous, Carolyn M., Severina, Inna I., Skulachev, Vladimir P., Kjaergaard, Henrik G., Smith, Robin A. J., Murphy, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635440/
https://ncbi.nlm.nih.gov/pubmed/16948637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060919
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