Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore

A unique phenomenon of mitochondria-targeted protonophores is described. It consists in a transmembrane H(+)-conducting fatty acid cycling mediated by penetrating cations such as 10-(6’-plastoquinonyl)decyltriphenylphosphonium (SkQ1) or dodecyltriphenylphosphonium (C(12)TPP). The phenomenon has been...

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Bibliografische gegevens
Hoofdauteurs: Severin, Fedor F., Severina, Inna I., Antonenko, Yury N., Rokitskaya, Tatiana I., Cherepanov, Dmitry A., Mokhova, Elena N., Vyssokikh, Mikhail Yu., Pustovidko, Antonina V., Markova, Olga V., Yaguzhinsky, Lev S., Korshunova, Galina A., Sumbatyan, Nataliya V., Skulachev, Maxim V., Skulachev, Vladimir P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818959/
https://ncbi.nlm.nih.gov/pubmed/20080732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910216107
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