A Divergent SAR Study Allows Optimization of a Potent 5-HT(2c) Inhibitor to a Promising Antimalarial Scaffold

Yazar: Calderón, Félix, Vidal-Mas, Jaume, Burrows, Jeremy, de la Rosa, Juan Carlos, Jiménez-Díaz, María Belén, Mulet, Teresa, Prats, Sara, Solana, Jorge, Witty, Michael, Gamo, Francisco Javier, Fernández, Esther
Baskı/Yayın Bilgisi 2012

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS

Yazar: Calderón, Félix, Barros, David, Bueno, José María, Coterón, José Miguel, Fernández, Esther, Gamo, Francisco Javier, Lavandera, José Luís, León, María Luisa, Macdonald, Simon J. F., Mallo, Araceli, Manzano, Pilar, Porras, Esther, Fiandor, José María, Castro, Julia
Baskı/Yayın Bilgisi 2011

Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites

Yazar: Matralis, Alexios N., Malik, Adnan, Penzo, Maria, Moreno, Inmaculada, Almela, Maria J., Camino, Isabel, Crespo, Benigno, Saadeddin, Anas, Ghidelli-Disse, Sonja, Rueda, Lourdes, Calderon, Felix, Osborne, Simon A., Drewes, Gerard, Böesche, Markus, Fernández-Álvaro, Elena, Martin Hernando, Jose Ignacio, Baker, David A.
Yayımlandı J Med Chem (2019)

A New In Vivo Screening Paradigm to Accelerate Antimalarial Drug Discovery

Yazar: Jiménez-Díaz, María Belén, Viera, Sara, Ibáñez, Javier, Mulet, Teresa, Magán-Marchal, Noemí, Garuti, Helen, Gómez, Vanessa, Cortés-Gil, Lorena, Martínez, Antonio, Ferrer, Santiago, Fraile, María Teresa, Calderón, Félix, Fernández, Esther, Shultz, Leonard D., Leroy, Didier, Wilson, David M., García-Bustos, José Francisco, Gamo, Francisco Javier, Angulo-Barturen, Iñigo
Baskı/Yayın Bilgisi 2013

A high throughput screen for next-generation leads targeting malaria parasite transmission

Yazar: Delves, Michael J., Miguel-Blanco, Celia, Matthews, Holly, Molina, Irene, Ruecker, Andrea, Yahiya, Sabrina, Straschil, Ursula, Abraham, Matthew, León, María Luisa, Fischer, Oliver J., Rueda-Zubiaurre, Ainoa, Brandt, Jochen R., Cortés, Álvaro, Barnard, Anna, Fuchter, Matthew J., Calderón, Félix, Winzeler, Elizabeth A., Sinden, Robert E., Herreros, Esperanza, Gamo, Francisco J., Baum, Jake
Yayımlandı Nat Commun (2018)

Case Study of Small Molecules As Antimalarials: 2-Amino-1-phenylethanol (APE) Derivatives

Yazar: Chaparro, María J., Vidal, Jaume, Angulo-Barturen, Íñigo, Bueno, José M., Burrows, Jeremy, Cammack, Nicholas, Castañeda, Pablo, Colmenarejo, Gonzalo, Coterón, José M., de las Heras, Laura, Fernández, Esther, Ferrer, Santiago, Gabarró, Raquel, Gamo, Francisco J., García, Mercedes, Jiménez-Díaz, María B., Lafuente, María J., León, María L., Martínez, María S., Minick, Douglas, Prats, Sara, Puente, Margarita, Rueda, Lourdes, Sandoval, Elena, Santos-Villarejo, Ángel, Witty, Michael, Calderón, Félix
Baskı/Yayın Bilgisi 2014

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Yazar: Williamson, Alice E., Ylioja, Paul M., Robertson, Murray N., Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B., Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N., Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A., Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L., Delves, Michael, Dennis, Adelaide S. M., Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J., Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P., Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A., Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J., Thomson, Patrick, Turner, Peter, Wallace, Iain M., Wells, Timothy N. C., White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A., Wittlin, Sergio, Todd, Matthew H.
Yayımlandı ACS Cent Sci (2016)