Case Study of Small Molecules As Antimalarials: 2-Amino-1-phenylethanol (APE) Derivatives

[Image: see text] Antiparasitic oral drugs have been associated to lipophilic molecules due to their intrinsic permeability. However, these kind of molecules are associated to numerous adverse effects, which have been extensively studied. Within the Tres Cantos Antimalarial Set (TCAMS) we have ident...

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Päätekijät: Chaparro, María J., Vidal, Jaume, Angulo-Barturen, Íñigo, Bueno, José M., Burrows, Jeremy, Cammack, Nicholas, Castañeda, Pablo, Colmenarejo, Gonzalo, Coterón, José M., de las Heras, Laura, Fernández, Esther, Ferrer, Santiago, Gabarró, Raquel, Gamo, Francisco J., García, Mercedes, Jiménez-Díaz, María B., Lafuente, María J., León, María L., Martínez, María S., Minick, Douglas, Prats, Sara, Puente, Margarita, Rueda, Lourdes, Sandoval, Elena, Santos-Villarejo, Ángel, Witty, Michael, Calderón, Félix
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060931/
https://ncbi.nlm.nih.gov/pubmed/24944739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500015r
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